USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: Q04695 USC-OGP 2-DE database:  Q04695 Q04695 General information about the entry View entry in simple text format Entry name K1C17_HUMAN Primary accession number Q04695 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Keratin, type I cytoskeletal 17; AltName: Full=39.1; AltName: Full=Cytokeratin-17; Short=CK-17; AltName: Full=Keratin-17; Short=K17;. Gene name Name=KRT17 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1188: pI=6.62; Mw=42327 SPOT OGP-1192: pI=5.85; Mw=41038 Cross-references UniProtKB/Swiss-Prot Q04695; K1C17_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name K1C17_HUMAN Primary accession number Q04695 Secondary accession number(s) A5Z1M9 A5Z1N0 A5Z1N1 A5Z1N2 A6NDV6 A6NKQ2 Q6IP98 Q8N1P6 Sequence was last modified on  January 23, 2007 (version 2) Annotations were last modified on  March 15, 2017 (version 176) Name and origin of the protein Description RecName: Full=Keratin, type I cytoskeletal 17; AltName: Full=39.1; AltName: Full=Cytokeratin-17; Short=CK-17; AltName: Full=Keratin-17; Short=K17; Gene name Name=KRT17 Encoded on Name=KRT17 Keywords Coiled coil; Complete proteome; Cytoplasm; Disease mutation; Ectodermal dysplasia; Intermediate filament; Isopeptide bond; Keratin; Palmoplantar keratoderma; Phosphoprotein; Reference proteome; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL Z19574; CAA79626.1; -; Genomic_DNA EMBL X62571; CAA44451.1; -; mRNA EMBL AK095342; BAC04534.1; -; mRNA EMBL AC022596; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AL353997; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL BC000159; AAH00159.2; -; mRNA EMBL BC011901; AAH11901.1; -; mRNA EMBL BC056421; AAH56421.1; -; mRNA EMBL BC072018; AAH72018.1; ALT_FRAME; mRNA EMBL BC072019; AAH72019.1; -; mRNA EMBL S78515; AAB34565.1; -; Genomic_DNA EMBL EF608068; ABQ96595.1; -; mRNA EMBL EF608069; ABQ96596.1; -; mRNA EMBL EF608070; ABQ96597.1; -; mRNA EMBL EF608071; ABQ96598.1; -; mRNA CCDS CCDS11402.1; -; . PIR S30433; S30433; . RefSeq NP_000413.1; NM_000422.2; . UniGene Hs.2785; -; . ProteinModelPortal Q04695; -; . SMR Q04695; -; . BioGrid 110070; 35; . DIP DIP-33093N; -; . IntAct Q04695; 14; . MINT MINT-256746; -; . STRING 9606.ENSP00000308452; -; . iPTMnet Q04695; -; . PhosphoSitePlus Q04695; -; . SwissPalm Q04695; -; . BioMuta KRT17; -; . DMDM 547751; -; . SWISS-2DPAGE Q04695; -; . EPD Q04695; -; . PaxDb Q04695; -; . PeptideAtlas Q04695; -; . PRIDE Q04695; -; . TopDownProteomics Q04695; -; . DNASU 3872; -; . Ensembl ENST00000311208; ENSP00000308452; ENSG00000128422; . GeneID 3872; -; . KEGG hsa:3872; -; . UCSC uc002hxh.3; human; . CTD 3872; -; . DisGeNET 3872; -; . GeneCards KRT17; -; . GeneReviews KRT17; -; . H-InvDB HIX0059686; -; . HGNC HGNC:6427; KRT17; . HPA CAB000029; -; . HPA HPA000452; -; . HPA HPA000453; -; . HPA HPA000539; -; . HPA HPA045062; -; . MalaCards KRT17; -; . MIM 148069; gene; . MIM 167210; phenotype; . MIM 184500; phenotype; . neXtProt NX_Q04695; -; . OpenTargets ENSG00000128422; -; . Orphanet 2309; Pachyonychia congenita; . Orphanet 841; Sebocystomatosis; . PharmGKB PA30214; -; . eggNOG ENOG410IFTF; Eukaryota; . eggNOG ENOG410Y9IV; LUCA; . GeneTree ENSGT00760000118808; -; . HOVERGEN HBG013015; -; . InParanoid Q04695; -; . KO K07604; -; . OMA QYHRTIE; -; . OrthoDB EOG091G087I; -; . PhylomeDB Q04695; -; . TreeFam TF332742; -; . Reactome R-HSA-6805567; Keratinization; . Reactome R-HSA-6809371; Formation of the cornified envelope; . GeneWiki Keratin_17; -; . GenomeRNAi 3872; -; . PMAP-CutDB Q04695; -; . PRO PR:Q04695; -; . Proteomes UP000005640; Chromosome 17; . Bgee ENSG00000128422; -; . ExpressionAtlas Q04695; baseline and differential; . Genevisible Q04695; HS; . GO GO:0071944; C:cell periphery; IEA:Ensembl; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005882; C:intermediate filament; TAS:ProtInc; . GO GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA; . GO GO:0042289; F:MHC class II protein binding; IPI:UniProtKB; . GO GO:0032395; F:MHC class II receptor activity; IDA:UniProtKB; . GO GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc; . GO GO:0070268; P:cornification; TAS:Reactome; . GO GO:0008544; P:epidermis development; TAS:ProtInc; . GO GO:0031069; P:hair follicle morphogenesis; ISS:UniProtKB; . GO GO:0045109; P:intermediate filament organization; IEA:Ensembl; . GO GO:0031424; P:keratinization; TAS:Reactome; . GO GO:0030307; P:positive regulation of cell growth; IEA:Ensembl; . GO GO:0051798; P:positive regulation of hair follicle development; IEA:Ensembl; . GO GO:0045727; P:positive regulation of translation; IEA:Ensembl; . GO GO:0007165; P:signal transduction; IMP:UniProtKB; . InterPro IPR001664; IF; . InterPro IPR018039; Intermediate_filament_CS; . InterPro IPR002957; Keratin_I; . InterPro IPR009053; Prefoldin; . PANTHER PTHR23239; PTHR23239; 1; . Pfam PF00038; Filament; 1; . PRINTS PR01248; TYPE1KERATIN; . SMART SM01391; Filament; 1; . SUPFAM SSF46579; SSF46579; 1; . PROSITE PS00226; IF; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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